Noscapine is an alkaloid obtained from poppy plants. It is used in the pharmaceutical industry as an anti-tussive or cough suppressing agent. Noscapine does not possess pain killing properties, however, it is known to alleviate cough. It is also known as narcotine, anarcotine, nectodon, nospen and opiane among others. Noscapine is used as an over-the-counter cough suppressant and is known to be a sleep inducer. It has anti-inflammatory effect owing to which it is found to be effective to relieve stressed throat muscles resulting from throat infection. Noscapine suppresses cold by thinning and loosening mucus in the airways, clearing congestion and by making breathing easier.
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The growing demand for cough suppressants from the healthcare and pharmaceutical industry has been propelling the growth of noscapine base. Additionally, the use of noscapine for the treatment of pollution related health disorders such as dust allergies, seasonal cold and cough attacks has been responsible for the growth of this market. However, a doctor’s prescription is necessary for the sale of this drug due to the widespread the abuse of noscapine base as a recreational drug. Noscapine base is being studied for its use as an anti-cancer drug which is expected to open new avenues for noscapine market within the forecast period.
Asia Pacific, North America and Western Europe are the leading regions in terms of noscapine manufacturing and use. The generic drugs market in the Asia Pacific countries such as China and India has been a major producer of noscapine base. However, countries such as the U.S and the Netherlands have laid down stringent regulations for the sale of this drug. The overdose of noscapine does not cause any major side-effects; however, it is responsible for causing hallucination owing to which it is abused in many regions of the world. Treatment of cough using morphine and codeine compete with noscapine. The three compounds are derived from poppy plant however, noscapine is anti addictive owing to which it is a preferred cough suppressant compared to morphine and codeine derived cough syrups.
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This drug is not prescribed during pregnancy and in cases of hypersensitivity of noscapine base Internationally, noscapine is known by the following trade names: Asthphyllin, Sekiel, , Noscapine Hcl Katwijk, Tossamin, Capval, Longatin, Demotussil, Noskapin Dak, Noskapin, Roter Noscapect ,Mercotin, Nosca Mereprine, Narcotine, Nipaxon, Noscaflex, Tuscalman Berna, Noscapina, Noscapine Hcl Ratiopharm, Noscapine Hcl San, Noscapine, Noskapin Aco, Noscapine Hcl Kring ,Coflin, Hoestdrank Noscapine Hcl, Noscaflex, Noscapine Hcl Pch, Noscapine Hcl Sandoz, Tuscalman, Tuscalman, Tussanil-N and Nitepax.
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